CBMA

10:00

Receção e Entrega de Documentação/ Registration

11:00 - 11:20

Sessão de Abertura/ Opening session

Maria João Sousa (Presidente da Comissão de Organização)

Cândida Lucas (Diretora do IB-S)

Jorge Pedrosa (Diretor do ICVS)

Fernanda Cássio (Diretora do CBMA)

11:20 – 12:20

Conferência "Professor Nicolau van Uden"

Moderadores: Mª da Conceição Loureiro Dias e Cecília Leão

Dos fungos filamentosos aos unicelulares e das vinhas aos hospitais: espectro de um fungicida de última geração

Virgílio Loureiro

Sessão I / Session I - Exploring Yeast Diversity for Biotechnology

Moderadores: Arlete Mendes-Ferreira e Madalena Oom

12:20-12:35

A genomic and phenotypic characterization of a lineage of Saccharomyces cerevisiae associated with olive brine

Ana Pontes, Paula Gonçalves and José Paulo Sampaio

12:35-12:50

Development of potential yeast protein extracts for wine clarification and stabilization

Leonor Gaspar, Amadeu Machado, Rute Coutinho, Adriana Xavier, Manuel Figueiredo, Victor Freitas, Maria de Fátima Teixeira, Filipe Centeno and João Simões

13:00-14:30

Almoço/ Lunch

Sessão II / Session II - Exploring Yeast Diversity for Biotechnology (cont.)

Moderadores: José Paulo Sampaio e Catarina Prista

14:30-14:45

Genome sequence of the non-conventional wine yeast Hanseniaspora guilliermondii UTAD222 unveils relevant traits of this species and of the Hanseniaspora genus in the context of wine fermentation

Isabel Seixas, C. Barbosa, A. Mendes-Faia, U. Güldener, R. Tenreiro, A. Ferreira* and N. P. Mira*

14:45-15:00

Exploring organic acid producer microorganisms – Identification, morpho- and physiological characterization of wild yeast strains

Maria Sousa-Silva, David Ribas, Ricardo Franco-Duarte, Célia Pais, Margarida Casal and Isabel Soares-Silva

15:00-15:15

Yeasts as biocontrol agents of fungal phytopathogenic diseases

Pedro Ferraz, Mariana Rodrigues, Fernanda Cássio and Cândida Lucas

15:15-15:30

Port and Douro Wines Institute, IP (IVDP) Yeast Culture Collection

Margarida Roseira, Natália Ribeiro, Vitória Maciel and Maria João Sousa

Sessão III/ / Session III – Yeast Physiology and Genetics

Moderadores: Paula Gonçalves e Isabel Soares-Silva

15:30-15:45

Impact of horizontal gene transfer on sugar metabolism in a fructophilic yeast lineage

Carla Gonçalves, Madalena Oom, Maria José Leandro and Paula Gonçalves

15:45-16:00

Dephosphorylation of the ATP synthase subunit Atp2 by the Ser/Thr protein phosphatase Sit4p contributes to the regulation of mitochondrial function

Clara Pereira, Andreia T. Pereira, Hugo Osório, Pedro Moradas-Ferreira and Vítor Costa

16:00-16:15

Copper detoxification in yeast – a new link with iron homeostasis and Fe-S biogenesis

Ana Gaspar?Cordeiro*, Soraia Marques Caetano*, Catarina Amaral*, Claudina Rodrigues?Pousada*, Catarina Pimentel

16:15-16:30

Pkh1-dependent activation of Ypk1 is triggered by membrane stress in a yeast model of Niemann-Pick type C1 disease

Rúben Gonçalves, Vasco Fontes, Vítor Costa and Rita Vilaça

16:30 -17:00

Café/ /Coffee Break

Sessão IV / Session IV – Yeast Cell Death and Aging

Moderadores: Pedro Moradas-Ferreira e Vítor Costa

17:00-17:15

Pkh1p-Ypk1p and Pkh1p-Sch9p pathway activation underlies mitochondrial-dependent regulated cell death induced by acetic acid

António Rego, Katrina F. Cooper, Justin Snider, Yusuf A. Hannun, Vítor Costa, Manuela Côrte-Real, and Susana Rodrigues Chaves

17:15-17:30

Characterization of the yeast cell death induced by a benzo[a]phenoxazine derivative

João C. Ferreira, C. Lopes, A. Almeida, A. Preto, M. S. T. Gonçalves and Maria J. Sousa

17:30-17:45

Deciphering the mechanisms underlying bovine milk lactoferrin anticancer activity using yeast and cancer cell lines as complementary models

Cátia S. Pereira, Joana P. Guedes, Susana R. Chaves, María T. Andrés, José F. Fierro, Hernâni Gerós, Lígia R. Rodrigues and Manuela Côrte-Real

17:45-18:00

Caloric restriction rescues aged yeast cells from ?-synuclein toxicity through regulation of proteolytic systems

Belém Sampaio-Marques, Hélder R. Pereira and Paula Ludovico

18:00-18:15

Impact of nutrients in longevity regulation of the yeast Saccharomyces cerevisiae

Júlia Santos, Maria João Sousa, Cecília Leão and George van der Merwe

18:15-18:45

Apresentações FLASH / FLASH Presentations

Moderadores: Sandra Paiva e Paula Ludovico

Understanding the molecular mechanisms of homothallism in the order Cystofilobasidiales

Alexandra Cabrita, Márcia David-Palma, Marco A. Coelho, José Paulo Sampaio and Paula Gonçalves

High-throughput screening of oleaginous yeasts by using innovative fluorimetric and spectroscopic approaches

Catarina Miranda, Sara Bettencourt, Tatiana Pozdniakova, Raul Machado, Paula Sampaio, Ricardo Franco-Duarte and Célia Pais

Volatile fatty acids as carbon source for single cell oil production by oleaginous yeasts

Sara Bettencourt, Catarina Miranda, Tatiana Pozdniakova, Paula Sampaio, Ricardo Franco-Duarte and Célia Pais

Candida albicans Cht3 as a novel recombinant subunit antigen against fungal infections: characterisation and liposomal encapsulation

Augusto Costa-Barbosa, M. Dias, M.E.C.D.R. Oliveira, T. Collins and P. Sampaio

Microbiome shift in the context of recurrent vulvovaginal candidosis (RVVC): a new biomarker for recurrence?

Joana Rolo, C. Gaspar, P. Gonçalves-Faria, T. Barata, J. Martinez-de-Oliveira and A. Palmeira-de-Oliveira

Quantitative assessment of DNA damage in the industrial ethanol production strain Saccharomyces cerevisiae PE-2

Paulo César Silva, Lucilia Domingues, Tony Collins, Rui Oliveira and Björn Johansson

20:00

Jantar das Leveduras/ Yeast Dinner

Restaurante CENTURIUM

Sessão V/ Session V- Yeast and Human Health I

Moderadores: Nuno Mira e Paula Sampaio

9:00-9:15

Candida albicans overcolonization of the elderly gut: Involvement of adenosine A2A receptors

Lisa Rodrigues, Isabel Miranda, Geanne Andrade, Marta Mota, Luísa Cortes, Acácio Rodrigues, Rodrigo Cunha and Teresa Gonçalves

9:15-9:30

New multiplex PCR based methodology for the diagnosis of Candida and Aspergillus species

Joana Carvalho-Pereira, Jan Springer, Maria José Buítrago, Jurgen Löffler, Célia Pais and Paula Sampaio

9:30-9:45

Beyond MDR transporter-mediated azole resistance in Candida glabrata: functional characterization of the transcription factors CgRpn4 and CgMrr1

Pedro Pais, Mónica Galocha, Raquel Califórnia, Geraldine Butler and Miguel Cacho Teixeira

9:45-10:00

Alternative carbon sources modulate Candida glabrata biofilm development on medical devices

Alexandra Gomes-Gonçalves, Rosana Alves, M. Casal, Patrick Van Dijck and Sandra Paiva

10:00-11:30

Café e Posters / Coffee and Posters

Molecular mechanisms of chronological lifespan modulation

Hélder Pereira, Alexandra Teixeira, Belém Sampaio-Marques and Paula Ludovico

The versatile role of mannitol in central metabolism of the fructophilic yeast Starmerella bombicola

Carolina Ferreira, Carla Gonçalves and Paula Gonçalves

Semen supports growth of Candida albicans: a possible role of this pathogen in infertility?

Caixeirinho P., J.Rolo, P.Ruivo-Gomes, C.Gaspar, R.Palmeira-de-Oliveira , J.Martinez-de-Oliveira and A. Palmeira-de-Oliveira

Exposure of recurrent vulvovaginal Candida spp isolates to azole compounds prevents biofilm formation?

Faria-Gonçalves P., J. Rolo, C. Gaspar, A. S. Oliveira, T. Barata, J. Martinez-de-Oliveira, and A. Palmeira-de-Oliveira

Functional characterization of Cyberlindnera jadinii carboxylate transporters in Saccharomyces cerevisiae

Maria Sousa-Silva, David Ribas, Margarida Casal and Isabel Soares-Silva

Towards a genetic toolkit for Sporothrix brasiliensis analysis

Beatriz H Ferreira, Gabriela Neves, Jorge H Ramírez-Prado, Paula Sampaio, Célia Pais, Maria SS Felipe, Gustavo Goldman, Agostinho Carvalho, Leila Bezerra, Cristina Cunha and Fernando Rodrigues

The Ady2 “NPAPLGL(M/S)” motif is critical for acetate uptake and binding

David Ribas, Isabel Soares-Silva, Daniel Vieira, Maria Sousa-Silva, Joana Sá-Pessoa, João Azevedo-Silva, Sandra Cristina Viegas, Cecília Maria Arraiano, Sandra Paiva, Pedro Soares and Margarida Casal

Assessing yeast diversity in Portuguese honey samples

Cláudia Carvalho, Céline Freitas & José Paulo Sampaio

Fostering the utilization of Non-Saccharomyces yeasts as co-adjuvants of wine and beer fermentations through the exploration of comparative genomics data

Maria J. Tavares, Ulrich Guldener, Arlete Mendes Ferreira, Alexandra M. Ferreira and Nuno P. Mira

Saccharomyces cerevisiae as a model system to uncover target and off-target effects of fungicides of environmental concern

Carla Carvalho, Maria João Sousa, Bruno B. Castro and Susana R. Chaves

Exploring yeast as a tool to study the human pro-apoptotic protein Bax

Vitória Baptista, Cátia S. Pereira, Joana P. Guedes, Maria João Sousa, Susana Chaves and Manuela Côrte-Real

Evaluation of decolourisation of textile dyes by selected yeasts

Marta Mendes, Patrícia Moreira, Paula Castro and Manuela Pintado

Polyphasic identification of a yeast isolate with dye decolourisation ability

C. Neto, M. M. Pintado and P. Moreira

Role of vacuolar membrane proteins in acetic acid-induced cell death

Joana Terra-Matos, Cátia S. Pereira, Susana R. Chaves, Maria João Sousa, Hernâni Gerós, Manuela Côrte-Real

Unveilling the Candida cylindracea genome to study the role of the translational machinery on gene evolution

Rita Coimbra, Miguel Pinheiro, Andreia Reis, Ana R Bezerra, Gabriela Moura, Manuel

The role of ER-mitochondria contact sites in acetic acid-induced cell death

Vítor Martins, Tânia Fernandes, Catarina Afonso, Diana Lopes, Rosário Domingues, Manuela Côrte-Real and Maria João Sousa

 Sessão VI/ SessionVI - Yeast and Human Health II

Moderadores: Fernando Rodrigues e Célia Pais

11:30-11:45

The role of Candida albicans transcription factor RLM1 in response to carbon adaptation

João Oliveira-Pacheco*, Rosana Alves*, Augusto Costa Barbosa, B. Cerqueira-Rodrigues, P. Pereira-Silva, Sandra Paiva, Sónia Silva, Mariana Henriques, Célia Pais and Paula Sampaio

11:45-12:00

Genomic adaptative mechanisms mediating azole resistance and adaptation to the human host in Candida glabrata, with emphasis on the role of CgPDR1 regulon

Sara B. Salazar, Tiago Pedreira, Hiroji Chibana, Maria M. Lopes, Ulrich Güldener and Nuno P. Mira

12:00-12:15

Study of the interaction between vaginal lactobacilli, Candida albicans and Candida glabrata: from physiological aspects to transcriptomic analyses

Nuno A. Pedro and Nuno P. Mira

12:15-12:45

Microbial Resource Research Infrastructure (MIRRI) and the Portuguese microBiological Resource Center Network (Pt-mBRCN): the current situation and future perspectives

Nelson Lima and José Paulo Sampaio

12:45-14:15

Almoço/ Lunch

Sessão VII / Session VII - Study of Transporters in Yeast

Moderadores: Margarida Casal e Isabel Sá Correia

14:15-14:35

                                     in memorium of André Goffeau

14:35-14:50

Understanding the role of grapevine NIPs aquaporins in transport of water, glycerol and atypical substrates in aqy-null Saccharomyces cerevisiae

Farzana Sabir, Maria Loureiro-Dias, Graça Soveral and Catarina Prista

14:50-15:05

Functional characterization of the Human Copper Transporters hCTR1 and hCTR2 in the yeast Saccharomyces cerevisiae

Cláudia Barata-Antunes, A. B. Figueiredo, G. Talaia, R. Alves, A. M. Fernandes, V. Martins, P. A. De Beule, H. Gerós and S. Paiva

15:05-15:20

The relationship between structure and function in the Acetate transporter family

João Azevedo-Silva*, Davide Castagnoli, David Ribas, Isabel Soares-Silva, Diogo Athayde, Margarida Archer and Margarida Casal

15:20-15:35

Yeast as model organism to study plant solute transporters

Richard Breia, Artur Conde, Henrique Noronha, Viviana Martins, Hernâni Gerós

15:35-16:25

Conferência “Jovem Investigador”

Tributo à Professora Isabel Spencer-Martins

/ "Young Researcher" Conference -Tribute to Professor Isabel Spencer Martins 

Moderador: Manuela Côrte-Real

Deciphering genomic and pheno-metabolomic determinants of yeasts towards adaptation to different ecological niches and potential use in biotechnology

Ricardo Franco-Duarte

16:25-16:45

Sessão de Encerramento/ Closing session

Lanche | Partida / Coffee and Farewell